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Genesis Therapeutics

Research Associate - Biophysics

Genesis Therapeutics uses an advanced molecular AI platform (GEMS) to discover and design breakthrough medicines for challenging targets with unprecedented potency and selectivity.

scienceonsiteSan Diego, CAfull-time

Education Requirements:

  • B.S./M.S. in Biochemistry, Biophysics, or a related field

Experience Requirements:

  • minimum 1 year of academic or industry lab experience.

Responsibilities:

  • Design and execute routine biophysical assays from beginning to end using methods such as SPR, DSF, and other biophysical techniques to characterize small molecule-protein interactions.

  • Routinely and independently analyze & QC experimental data.

  • Program, validate, and operate liquid-handling automation (Biomek Liquid handler, Multidrop Combi, Integra Viaflo & Voyager) for 384-well plate-based assays and use instrumentation such as plate readers for reproducible, publication-quality data generation.

  • Communicate results efficiently & precisely in written format by maintaining electronic lab notebook.

  • Presents work to supervisor, lab and/or project meeting.

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Genesis Therapeutics

Senior Research Associate/Scientist – Immunology and Inflammation

Genesis Therapeutics uses an advanced molecular AI platform (GEMS) to discover and design breakthrough medicines for challenging targets with unprecedented potency and selectivity.

scienceonsiteSan Diego, CAfull-time

Benefits:

  • Competitive Pay

  • Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees)

  • Stock Option Eligibility

  • 401(k) Plan

  • Open PTO Policy Paid Company Holidays Free lunch and snacks at our offices

Education Requirements:

  • A BSc, MSc, or PhD degree in immunology, molecular and cell biology, biochemistry or a related field

Experience Requirements:

  • 8+, 5+ or 2+ years of relevant industry experience, respectively.

Responsibilities:

  • Autonomously plan, design, and execute biochemical and cell-based experiments to support our I&I pipeline.

  • Maintain a hands-on approach while being an open-minded, flexible team player.

  • Analyze, interpret and integrate complex datasets across multiple assay types.

  • Document data meticulously using ELN and state-of-the-art analyses.

  • Stay at the forefront of latest research through literature review and critical evaluation of available data sources.

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Genesis Therapeutics

Senior / Principal CADD Scientist

Genesis Therapeutics uses an advanced molecular AI platform (GEMS) to discover and design breakthrough medicines for challenging targets with unprecedented potency and selectivity.

scienceonsiteSan Diego, CAfull-time

Benefits:

  • Competitive Pay

  • Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees)

  • Stock Option Eligibility

  • 401(k) Plan

  • Open PTO Policy Paid Company Holidays Free lunch and snacks at our offices

Education Requirements:

  • PhD in Computational Chemistry, Structural Biology, or a related field.

Experience Requirements:

  • Minimum of 1-2 years of industry experience as a CADD scientist in pharma or biotech, with hands-on experience in active drug discovery programs.

Responsibilities:

  • Utilize a combination of industry-standard and proprietary AI-powered CADD tools to guide small molecule drug discovery programs across a diverse target portfolio, including novel targets with limited chemical precedents.

  • Use approaches like virtual screening, molecular simulation, and potency and ADMET prediction to support key decision-making in drug discovery efforts.

  • Collaborate closely with medicinal chemists in molecular design and the development of project-specific computational approaches.

  • Act as a cross-team connector, effectively communicating between our computational chemistry and medicinal chemistry teams to ensure seamless information flow and collaborative decision making.

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