Menten AI
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About
Menten AI is building the world's most advanced generative AI platform for peptide therapeutics. Their platform integrates physics-based design with generative machine learning to overcome traditional drug design limitations, such as small datasets and computationally expensive sampling. By creating its own data from first principles and applying machine learning, Menten AI guides the design and optimization of novel peptides, enabling the creation of drug-like chemical matter with high accuracy and efficiency. The platform can achieve desirable drug properties directly from in silico design, including nM potency, high plasma stability, cell-permeability, and oral bioavailability. Menten AI focuses on peptide macrocycles, delivering drug-like hit molecules in a single round of design in just 8 weeks, significantly faster than industry standards. Their platform has been validated across the preclinical discovery pipeline, demonstrating in vivo efficacy with several peptides.
Platform
Task
Features
• validated across preclinical discovery pipeline (in silico, in vitro, in vivo efficacy)
• 10,000x greater sampling power in 1/6 the time with >50% in vitro hit success
• designs peptide macrocycles in a larger chemical space and record time (8 weeks)
• achieves desirable drug properties from in silico design (nm potency, high plasma stability, cell-permeability, oral bioavailability)
• creates novel drug-like chemical matter efficiently and with high accuracy
• overcomes historical limitations in drug design
• physics-based design meets generative machine learning
• generative ai platform for peptide therapeutics
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