canSAR.ai
Click to visit website
About
canSAR.ai is a public, integrated knowledge-base for cancer drug discovery, powered by an international collaboration led by MD Anderson Cancer Center. It brings together multidisciplinary data across biology, chemistry, pharmacology, structural biology, cellular networks, and clinical annotations. Crucially, it applies machine learning and artificial intelligence to provide drug-discovery useful predictions. The platform offers tools like Chemical Search and Advanced Search for proteins, cell lines, drugs, diseases, and 3D structures. It serves as a single portal for complex multi-disciplinary questions, aiding hypothesis generation and decision-making in identifying causes, biomarkers, and therapeutics for cancer. It is freely available to all researchers.
Platform
Task
Features
• free and publicly available resource
• regularly updated multidisciplinary data (e.g., 3d structures, protein families)
• offers tools for analyzing tissue/cell line expression and structural data
• provides detailed insights on proteins, drugs, and their interactions
• advanced search across various biological and chemical entities
• chemical search (substructure and similarity)
• leverages ai/ml for drug-discovery predictions
• integrated knowledge-base for cancer drug discovery
FAQs
What is canSAR?
canSAR.ai is an integrated database that brings together biological, chemical, pharmacological (and eventually clinical) data to aid cancer research.
Do I need a license to use canSAR?
No, canSAR.ai is freely available to all cancer researchers, both academic and commercial.
Why is canSAR.ai called 'canSAR.ai'?
The name 'canSAR' is a historical play on words reflecting its integration of cancer-relevant data with compound Structure-Activity-Relationship (SAR) data.
I seem to find that some functionality is missing when using IE
Internet Explorer (IE) is a non-standards compliant browser. Use Microsoft Edge or other modern browsers for full functionality.
How can I inform you of any bugs or problems?
Please email us on cansar@mdanderson.org to report any bugs or issues you experience while using canSAR.
How can I cite canSAR?
You can cite canSAR using the publication: "canSAR: update to the cancer translational research and drug discovery knowledgebase" published in Nucl. Acids Res. in 2023.
Where does the data in canSAR.ai come from?
canSAR.ai data comes from a wide variety of public sources and publications. Internal versions also include internally generated experimental data.
How often is the data in canSAR.ai updated?
Data is generally updated on a monthly basis, but public sources have different cycles. The Data Sources page shows update status.
How frequently is the 3D structural data updated in canSAR?
3D structures are updated every week, a couple of days after PDB releases new structures, with additional annotations.
Do I need to know the official gene name to search for a target?
No, canSAR.ai searches all alternative names, synonyms, descriptions, and keywords.
What organisms does canSAR.ai store data on?
canSAR.ai focuses on human data for targets, but includes many model organism targets. Chemical screening data is from various organisms.
I still cannot find my target and I have searched for different names
Try expanding the search with "Advanced Search" and "All organisms." If still not found, try a sequence search or email cansar@mdanderson.org.
I cannot find a compound by searching for its name, but I expect it to be in canSAR
We annotate compound synonyms. Try a chemical structure search. If data is missing, contact us at cansar@mdanderson.org.
How do I find out what tissues or cell lines show high expression of my target?
View the Target Synopsis and go to the Expression area. For multiple targets, use the expression tool.
How do I find out if there is half life or other ADME data for my compound?
This information can be obtained from the "Compound Synopsis" Page for a given compound.
Pricing Plans
Free
Free Plan• Access to integrated knowledge-base
• Machine learning predictions
• Chemical Search
• Advanced Search (Protein, Cell Lines, Drugs & Compounds, Diseases, 3D Structures, Protein Families)
• Insights on protein expression and drug bioactivity
• Regularly updated data
• Full functionality without license
Job Opportunities
There are currently no job postings for this AI tool.
Ratings & Reviews
No ratings available yet. Be the first to rate this tool!
Alternatives
X-Chem
X-Chem accelerates small molecule drug discovery by combining DEL technology with AI solutions. Their ArtemisAI platform powers HITMiner for molecular interaction mapping and hit expansion.
View Details
BenevolentAI
BenevolentAI uses AI for drug discovery and development, partnering with pharma companies to tackle complex diseases and accelerate drug development timelines.
View Details
Aitia Bio
Aitia Bio uses AI, multi-omic data, and Gemini Digital Twins to accelerate drug discovery and development, focusing on oncology and neurodegenerative diseases.
View Details
Aganitha AI
Aganitha AI is an in silico company that partners with biopharma, personal & homecare, and material sciences industries, leveraging AI to accelerate scientific R&D.
View Details
MindRank AI
MindRank AI is an innovative platform leveraging machine learning, biology, and chemistry to push the boundaries of AI in small molecule drug discovery.
View DetailsFeatured Tools
GirlfriendGPT
NSFW AI chat platform with customizable characters, AI image generation, and voice chat. Explore roleplay and intimate interactions with AI companions.
View Details
xMates AI
xMates AI is a next-generation AI chat app powered by large language models, offering human-like interactions and roleplaying with customizable AI characters.
View Details
Promptix
Promptix is a macOS app that lets you run AI in any application with a hotkey. It helps you write faster, translate, polish text, and use custom prompts.
View Details
BestStock AI
BestStock AI is an AI-powered financial analysis platform, automating data processing and delivering predictive insights across financial instruments.
View Details
Wan 2.2
Wan 2.2 is an open-source AI video generation tool using MoE architecture, transforming text or images into professional 720P cinematic videos.
View Details
Wan 2.2 Animate
Wan 2.2 Animate is a free online AI tool that transforms any character with advanced AI-powered animations, precise facial expressions, and dynamic body movements without registration.
View Details
Soora2
Soora2 is a global Sora 2 AI video generation platform offering text-to-video, image-to-video, and AI editing tools without watermarks.
View Detailsnexos.ai
nexos.ai is an all-in-one AI platform for enterprises, enabling secure, organization-wide AI adoption, policy setting, and oversight for tech leaders.
View Details